DNA PLASTICITY AND DAMAGE IN AMYOTROPHIC LATERAL SCLEROSIS

DNA plasticity and damage in amyotrophic lateral sclerosis

The pathophysiology of amyotrophic lateral sclerosis (ALS) is particularly challenging due to the heterogeneity of its clinical presentation and the diversity of cellular, molecular and genetic peculiarities involved.Molecular insights unveiled several novel genetic factors to be inherent in both familial and sporadic disease entities, whose charac

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